


Jumping into a novel hostĪ successful jump into a novel host species is a three-step process. Here, we provide a brief overview of our current understanding of how and why pathogens evolve in novel host species, to guide an understanding of the potential evolutionary consequences of our control measures. Nevertheless, designing effective public health strategies to contain infectious outbreaks, particularly given other potentially conflicting interests (e.g. Steady advances in biology and medicine mean that we are now better at identifying pathogens of epidemic potential and at monitoring the spread of novel infections worldwide than ever before (e.g. The 21 st century has already had its share of outbreaks of zoonotic origin-SARS, MERS, Ebola, Hendra and Nipah-and the current COVID-19 pandemic has become a major international public health, social, economic and political crisis. For instance, several major pandemics have occurred in the last century that have killed millions of people, including the pandemics of 1918 H1N1 influenza, which partly originated in birds, and of HIV, which originated in chimpanzees. What needs to happen for a pathogen to successfully infect a new host species? This is a critical question given the devastation that emerging pathogens can cause.
